E. Antonio Chiocca, M.D., Ph.D.

Clinic  |  Research  |  Lab

Co-Director, Program for Interdisciplinary Neuroscience
Chair, Department of Neurosurgery
Harvey W. Cushing Professor of Neurosurgery, Harvard Medical School

Dr. Chiocca is Co-Director of the Brigham and Women’s Hospital (BWH) Program for Interdisciplinary Neuroscience. Dr. Chiocca also serves as Chair of the BWH Department of Neurosurgery and is the Harvey Cushing Professor of Neurosurgery at Harvard Medical School.

 

Previously, Dr. Chiocca was Chairman of the Department of Neurosurgery at the Ohio State University Medical Center. He has more than 250 peer-reviewed publications, including Nature Medicine, Nature Biotechnology, Molecular Cell, and PNAS.

 

Dr. Chiocca’s research has focused on how viruses with specific gene mutations will replicate selectively in tumors with a specific defect in a tumor suppressor pathway. His research has also included how modulation of innate immunity will improve replication of these tumor-selective viruses. More recently, Dr. Chiocca has elucidated how specific microRNAs (mir128 and mir451) regulate cellular target transcripts to permit tumor cell self-renewal and invasion into brain. He also has been the principal investigator of three multi-institutional clinical trials of gene-, viral-therapies for malignant gliomas, has been a permanent member of NIH study sections (NCI DT and NCI P01-D clinical studies), has been a member of the federal recombinant DNA Advisory Committee (RAC/OBA) and is currently a member of the NINDS Scientific Advisory Council.

 

In 2013, Dr. Chiocca was elected Vice President of the Society for Neuro-Oncology (SNO). In 2015, he was elected President of SNO. He is currently Treasurer of the American Academy of Neurological Surgery and is Chair of the Research Committee for the Society of Neurological Surgery. He also serves on the scientific advisory board of several foundations (Sontag, American Brain Tumor Association). He received The Grass Award in 2007, the Farber Award in 2008 and the Bittner Award in 2013. He was elected to the American Society for Clinical Investigation (2005), is an AAAS fellow (2005) and was also elected to the National Academy of Medicine (formerly Institute of Medicine) in 2014. He also has served on multiple editorial boards and is the current Tumor Section Editor for Neurosurgery. He was on the editorial board of Journal of Neurosurgery from 2005 until 2012.

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