The following is a list of recent papers that include data produced using the Studio’s resources:
2023:
Neuron, in. press
Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer’s disease brains
Andrew M. Stern, Yang Yang, Shanxue Jin, Keitaro Yamashita, Angela L. Meunier, Wen Liu, Yuqi Cai, Maria Ericsson, Lei Liu, Michel Goedert, Sjors H.W. Scheres, Dennis J. Selkoe
Science 2023 Mar 10
Droplet-based forward genetic screening of astrocyte-microglia cross-talk
Michael A Wheeler, Iain C Clark, Hong-Gyun Lee, Zhaorong Li, Mathias Linnerbauer, Joseph M Rone, Manon Blain, Camilo Faust Akl, Gavin Piester, Federico Giovannoni, Marc Charabati, Joon-Hyuk Lee, Yoon-Chul Kye, Joshua Choi, Liliana M Sanmarco, Lena Srun, Elizabeth N Chung, Lucas E Flausino, Brian M Andersen, Veit Rothhammer, Hiroshi Yano, Tomer Illouz, Stephanie E J Zandee, Carolin Daniel, David Artis, Marco Prinz, Adam R Abate, Vijay K Kuchroo, Jack P Antel, Alexandre Prat, Francisco J Quintana
Nature 2023 Feb
Identification of astrocyte regulators by nucleic acid cytometry
Iain C Clark, Michael A Wheeler, Hong-Gyun Lee, Zhaorong Li, Liliana M Sanmarco, Shravan Thaploo, Carolina M Polonio, Seung Won Shin, Giulia Scalisi, Amy R Henry, Joseph M Rone, Federico Giovannoni, Marc Charabati, Camilo Faust Akl, Dulce M Aleman, Stephanie E J Zandee, Alexandre Prat, Daniel C Douek, Eli A Boritz, Francisco J Quintana, Adam R Abate
Nature 2023 Jan;613(7944):550-557.
Metabolic regulation of species-specific developmental rates
Margarete Diaz-Cuadros, Teemu P Miettinen, Owen S Skinner, Dylan Sheedy, Carlos Manlio Díaz-García, Svetlana Gapon, Alexis Hubaud, Gary Yellen, Scott R Manalis, William M Oldham, Olivier Pourquié
J Neurochem 2023 Jan 10.
Lisa Brontesi, Thibaut Imberdis, Nagendran Ramalingam, Ulf Dettmer
Mol Ther Nucleic Acids 2023 Jan 2;31:265-275.
Secreted PGK1 and IGFBP2 contribute to the bystander effect of miR-10b gene editing in glioma
Yanhong Zhang, Rosalia Rabinovsky, Zhiyun Wei, Rachid El Fatimy, Evgeny Deforzh, Bai Luan, Leonid Peshkin, Erik J Uhlmann, Anna M Krichevsky
NPJ Parkinsons Dis 2023 Jan 16;9(1):4
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity
Nagendran Ramalingam, Shan-Xue Jin , Tim E Moors, Luis Fonseca-Ornelas, Kazuma Shimanaka, Shi Lei, Hugh P Cam, Aurelia Hays Watson, Lisa Brontesi, Lai Ding, Dinc Yasat Hacibaloglu, Haiyang Jiang, Se Joon Choi, Ellen Kanter, Lei Liu, Tim Bartels, Silke Nuber, David Sulzer, Eugene V Mosharov, Weisheng V Chen, Shaomin Li, Dennis J Selkoe, Ulf Dettmer
2022:
Nature 2022 Dec 21
Reconstruction and deconstruction of human somitogenesis in vitro
Yuchuan Miao, Yannis Djeffal, Alessandro De Simone, Kongju Zhu, Jong Gwan Lee, Ziqi Lu, Andrew Silberfeld, Jyoti Rao, Oscar A Tarazona, Alessandro Mongera, Pietro Rigoni, Margarete Diaz-Cuadros, Laura Min Sook Song, Stefano Di Talia, Olivier Pourquié
Nature 2022 Nov;611(7937):801-809.
Identification of environmental factors that promote intestinal inflammation
Liliana M Sanmarco, Chun-Cheih Chao, Yu-Chao Wang, Jessica E Kenison, Zhaorong Li , Joseph M Rone, Claudia M Rejano-Gordillo, Carolina M Polonio, Cristina Gutierrez-Vazquez, Gavin Piester, Agustin Plasencia, Lucinda Li, Federico Giovannoni, Hong-Gyun Lee, Camilo Faust Akl, Michael A Wheeler, Ivan Mascanfroni, Merja Jaronen, Moneera Alsuwailm, Patrick Hewson, Ada Yeste, Brian M Andersen, Diana G Franks, Chien-Jung Huang, Millicent Ekwudo, Emily C Tjon, Veit Rothhammer, Maisa Takenaka, Kalil Alves de Lima, Mathias Linnerbauer, Lydia Guo, Ruxandra Covacu, Hugo Queva, Pedro Henrique Fonseca-Castro, Maha Al Bladi, Laura M Cox, Kevin J Hodgetts, Mark E Hahn, Alexander Mildner, Joshua Korzenik, Russ Hauser, Scott B Snapper, Francisco J Quintana
Cell Rep 2022 Nov 22;41(8):111701.
Gemma L Johnson, Morgan B Glasser, Julia F Charles, Jeffrey Duryea, Jessica A Lehoczky
Cerebellum 2022 Oct 3;1-21.
Alain Ndayisaba, Ariana T Pitaro, Andrew S Willett, Kristie A Jones, Claudio Melo de Gusmao, Abby L Olsen, Jisoo Kim, Eero Rissanen, Jared K Woods, Sharan R Srinivasan, Anna Nagy, Amanda Nagy, Merlyne Mesidor, Steven Cicero, Viharkumar Patel, Derek H Oakley, Idil Tuncali, Katherine Taglieri-Noble, Emily C Clark, Jordan Paulson, Richard C Krolewski, Gary P Ho, Albert Y Hung, Anne-Marie Wills, Michael T Hayes, Jason P Macmore, Luigi Warren, Pamela G Bower, Carol B Langer, Lawrence R Kellerman, Christopher W Humphreys, Bonnie I Glanz, Elodi J Dielubanza, Matthew P Frosch, Roy L Freeman, Christopher H Gibbons, Nadia Stefanova, Tanuja Chitnis, Howard L Weiner, Clemens R Scherzer, Sonja W Scholz, Dana Vuzman, Laura M Cox, Gregor Wenning, Jeremy D Schmahmann, Peter Novak, Geoffrey S Young, Mel B Feany, Tarun Singhal, Vikram Khurana
Mol Neurodegener 2022 Sep 21;17(1):61.
Yi-Chen Hsieh, Joseph Negri, Amy He, Richard V Pearse 2nd, Lei Liu, Duc M Duong, Lori B Chibnik, David A Bennett, Nicholas T Seyfried, Tracy L Young-Pearse
NPJ Parkinsons Dis 2022 Sep 16;8(1):118.
Luis Fonseca-Ornelas, Jonathan M S Stricker, Stephanie Soriano-Cruz, Beatrice Weykopf, Ulf Dettmer, Christina R Muratore, Clemens R Scherzer, Dennis J Selkoe
Stem Cell Reports 2022 Sep 13;17(9):2111-2126.
Loss of endosomal exchanger NHE6 leads to pathological changes in tau in human neurons
Marty A Fernandez, Fatmata Bah, Li Ma, YouJin Lee, Michael Schmidt, Elizabeth Welch, Eric M Morrow, Tracy L Young-Pearse
Immunity 2022 Sep 13;55(9):1627-1644.e7.
Milica A Margeta, Zhuoran Yin, Charlotte Madore, Kristen M Pitts, Sophia M Letcher, Jing Tang, Shuhong Jiang, Christian D Gauthier, Sebastian R Silveira, Caitlin M Schroeder, Eleonora M Lad, Alan D Proia, Rudolph E Tanzi, David M Holtzman, Susanne Krasemann, Dong Feng Chen, Oleg Butovsky
Mol Cell 2022 Mar 29;S1097-2765(22)00256-8.
Evgeny Deforzh, Erik J Uhlmann, Eashita Das, Aleksandra Galitsyna, Ramil Arora, Harini Saravanan, Rosalia Rabinovsky, Aditya D Wirawan, Nadiya M Teplyuk, Rachid El Fatimy, Sucika Perumalla, Anirudh Jairam, Zhiyun Wei, Leonid Mirny, Anna M Krichevsky
Cell 2022 Jun 9;185(12):2035-2056.e33.
Erinc Hallacli, Can Kayatekin, Sumaiya Nazeen, Xiou H Wang, Zoe Sheinkopf, Shubhangi Sathyakumar, Souvarish Sarkar, Xin Jiang, Xianjun Dong, Roberto Di Maio, Wen Wang, Matthew T Keeney, Daniel Felsky, Jackson Sandoe, Aazam Vahdatshoar, Namrata D Udeshi, D R Mani, Steven A Carr, Susan Lindquist, Philip L De Jager, David P Bartel, Chad L Myers, J Timothy Greenamyre, Mel B Feany, Shamil R Sunyaev, Chee Yeun Chung, Vikram Khurana
NPJ Parkinsons Dis 2022 Jun 9;8(1):74.
Lipase regulation of cellular fatty acid homeostasis as a Parkinson’s disease therapeutic strategy
Saranna Fanning, Haley Cirka, Jennifer L Thies, Jooyoung Jeong, Sarah M Niemi, Joon Yoon, Gary P H Ho, Julian A Pacheco, Ulf Dettmer, Lei Liu, Clary B Clish, Kevin J Hodgetts, John N Hutchinson, Christina R Muratore, Guy A Caldwell, Kim A Caldwell, Dennis Selkoe
Nat Commun 2022 Jun 9;13(1):3317.
Mian Wang, Wanlu Li, Jin Hao, Arthur Gonzales 3rd, Zhibo Zhao, Regina Sanchez Flores, Xiao Kuang, Xuan Mu, Terry Ching, Guosheng Tang, Zeyu Luo, Carlos Ezio Garciamendez-Mijares, Jugal Kishore Sahoo, Michael F Wells, Gengle Niu, Prajwal Agrawal, Alfredo Quiñones-Hinojosa, Kevin Eggan, Yu Shrike Zhang
Neuron 2022 Jun 1;110(11):1806-1821.e8.
Human and mouse trigeminal ganglia cell atlas implicates multiple cell types in migraine
Lite Yang, Mengyi Xu, Shamsuddin A Bhuiyan, Jia Li, Jun Zhao, Randall J Cohrs, Justin T Susterich, Sylvia Signorelli, Ursula Green, James R Stone, Dan Levy, Jochen K Lennerz, William Renthal
Brain 2022 Jan 27
Andrew M Stern, Lei Liu, Shanxue Jin, Wen Liu, Angela L Meunier, Maria Ericsson, Michael B Miller, Megan Batson, Tingwan Sun, Sagar Kathuria, David Reczek, Laurent Pradier, Dennis J Selkoe
J Am Soc Nephrol 2022 Jan 28;ASN.2021020140.
Integrin α5 Is Regulated by miR-218-5p in Endothelial Progenitor Cells
Jialing Liu, Yi Li, Lingna Lyu, Liang Xiao, Aliza Anwar Memon, Xin Yu, Arvin Halim, Shivani Patel, Abdikheyre Osman, Wenqing Yin, Jie Jiang, Said Naini, Kenneth Lim, Aifeng Zhang, Jonathan Williams, Ruth Koester, Kevin Zeng Qi, Quynh-Anh Fucci, Lai Ding, Steven Chang, Ankit Patel, Yutaro Mori, Advika Chaudhari, Aaron Bao, Jia Liu, Tzongshi Lu, Andrew Siedlecki
Mol Psychiatry 2022 Feb 23.
Chun-I Wu, Elizabeth A Vinton, Richard V Pearse 2nd, Keunjung Heo, Aimee J Aylward, Yi-Chen Hsieh, Yan Bi, Sopefoluwa Adeleye, Seeley Fancher, Duc M Duong, Nicholas T Seyfried, Thomas L Schwarz , Tracy L Young-Pearse
J Neurosci 2022 Jan 26;
Arati Tripathi, Heba Alnakhala, Elizabeth Terry-Kantor, Andrew Newman, Lei Liu, Thibaut Imberdis, Saranna Fanning, Silke Nuber, Nagendran Ramalingam, Dennis Selkoe, Ulf Dettmer
Mol Cancer 2022 Jan 15;21(1):17.
A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing
Rachid El Fatimy, Yanhong Zhang, Evgeny Deforzh, Mahalakshmi Ramadas, Harini Saravanan, Zhiyun Wei, Rosalia Rabinovsky, Nadiya M Teplyuk, Erik J Uhlmann, Anna M Krichevsky
Immunity 2022 Jan 11;55(1):159-173.e9.
Danyang He, Heping Xu, Huiyuan Zhang, Ruihan Tang, Yangning Lan, Ruxiao Xing, Shaomin Li, Elena Christian, Yu Hou, Paul Lorello, Barbara Caldarone, Jiarui Ding, Lan Nguyen, Danielle Dionne, Pratiksha Thakore, Alexandra Schnell, Jun R Huh, Orit Rozenblatt-Rosen, Aviv Regev, Vijay K Kuchroo
2021:
Adv Healthc Mater 2021 Dec 31
Shreya Mehrotra, Bruna Alice Gomes de Melo, Mario Miscuglio, Kiavash Kiaee, Su Ryon Shin, Biman B Mandal
J Neuropathol Exp Neurol 2021 Dec 29;80(12):1117-1124.
Tumor-Derived Cell Culture Model for the Investigation of Meningioma Biology
Erik J Uhlmann, Rosalia Rabinovsky, Hemant Varma, Rachid El Fatimy, Ekkehard M Kasper, Justin M Moore, Rafael A Vega, Ajith J Thomas, Ronald L Alterman, Martina Stippler, Matthew P Anderson, Erik N Uhlmann, Franciela C Kipper, Anna M Krichevsky
Adv Mater 2021 Dec 21
Vertical Extrusion Cryo(bio)printing for Anisotropic Tissue Manufacturing
Zeyu Luo, Guosheng Tang, Hossein Ravanbakhsh, Wanlu Li, Mian Wang, Xiao Kuang, Carlos Ezio Garciamendez-Mijares, Liming Lian, Sili Yi, Junlong Liao, Maobin Xie, Jie Guo, Zongke Zhou, Yu Shrike Zhang
Adv Mater 2021 Oct 5;e2107038.
Digital Light Processing Based Bioprinting with Composable Gradients
Mian Wang, Wanlu Li, Luis S Mille, Terry Ching, Zeyu Luo, Guosheng Tang, Carlos Ezio Garciamendez, Ami Lesha, Michinao Hashimoto, Yu Shrike Zhang
Sci Adv 2021 Oct 29;7(44):eabk2775.
Eun-Bee Choi, Munender Vodnala, Madeleine Zerbato, Jianing Wang, Jaclyn J Ho, Carla Inouye, Lai Ding, Yick W Fong
Alzheimers Dement 2021 Sep 22. doi: 10.1002/alz.12457.
An ultra-sensitive immunoassay detects and quantifies soluble Aβ oligomers in human plasma
Lei Liu, Hyunchang Kwak, Trebor L Lawton, Shan-Xue Jin , Angela L Meunier , Yifan Dang , Beth Ostaszewski , Alison C Pietras, Andrew M Stern, Dennis J Selkoe
Neuron 2021 Aug 26;S0896-6273(21)00578-X.
Valentina N Lagomarsino, Richard V Pearse 2nd, Lei Liu, Yi-Chen Hsieh, Marty A Fernandez, Elizabeth A Vinton, Daniel Paull, Daniel Felsky, Shinya Tasaki, Chris Gaiteri, Badri Vardarajan, Hyo Lee, Christina R Muratore, Courtney R Benoit, Vicky Chou, Seeley B Fancher, Amy He, Julie P Merchant, Duc M Duong, Hector Martinez, Monica Zhou, Fatmata Bah, Maria A Vicent, Jonathan M S Stricker, Jishu Xu, Eric B Dammer, Allan I Levey, Lori B Chibnik, Vilas Menon, Nicholas T Seyfried, Philip L De Jager, Scott Noggle, Dennis J Selkoe, David A Bennett, Tracy L Young-Pearse
Nat Commun 2021 Aug 13;12(1):4907.
PD-L1 + and XCR1 + dendritic cells are region-specific regulators of gut homeostasis
Thais G Moreira, Davide Mangani, Laura M Cox, Jeffrey Leibowitz, Eduardo L C Lobo, Mariana A Oliveira, Christian D Gauthier, Brenda N Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C A Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C Anderson, Rafael M Rezende, Ana Maria C Faria, Howard L Weiner
Bio Protoc 2021 Aug 5;11(15):e4102.
Isolation of Nuclei from Mouse Dorsal Root Ganglia for Single-nucleus Genomics
Lite Yang, Ivan Tochitsky, Clifford J Woolf, William Renthal
Proc Natl Acad Sci USA 2021 Jul 13;118(28):e2022960118.
Ziad Al Tanoury, John F Zimmerman, Jyoti Rao, Daniel Sieiro, Harold M McNamara, Thomas Cherrier, Alejandra Rodríguez-delaRosa, Aurore Hick-Colin, Fanny Bousson, Charlotte Fugier-Schmucker, Fabio Marchiano, Bianca Habermann, Jérome Chal, Alexander P Nesmith, Svetlana Gapon, Erica Wagner, Vandana A Gupta, Rhonda Bassel-Duby, Eric N Olson, Adam E Cohen, Kevin Kit Parker, Olivier Pourquié
Elife2021 Jul 6;10:e64819.
Charlene Guillot, Yannis Djeffal, Arthur Michaut, Brian Rabe, Olivier Pourquié
Proc Natl Acad Sci U S A 2021 Jul 13;118(28):e2022960118.
Ziad Al Tanoury, John F Zimmerman, Jyoti Rao, Daniel Sieiro, Harold M McNamara, Thomas Cherrier, Alejandra Rodríguez-delaRosa, Aurore Hick-Colin, Fanny Bousson, Charlotte Fugier-Schmucker, Fabio Marchiano, Bianca Habermann, Jérome Chal, Alexander P Nesmith, Svetlana Gapon, Erica Wagner, Vandana A Gupta, Rhonda Bassel-Duby, Eric N Olson, Adam E Cohen, Kevin Kit Parker, Olivier Pourquié
Cell Rep2021 Jul 6;36(1):109333.
Luis Fonseca-Ornelas, Thibault Viennet, Matteo Rovere, Haiyang Jiang, Lei Liu, Silke Nuber, Maria Ericsson, Haribabu Arthanari, Dennis J Selkoe
Hum Mol Genet2021 Jul 12;ddab188.
Tae-Eun Kim, Andrew J Newman, Thibaut Imberdis, Lisa Brontesi, Arati Tripathi, Nagendran Ramalingam, Saranna Fanning, Dennis Selkoe, Ulf Dettmer
Nat Med2021 Jul;27(7):1212-1222.
Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease
Benjamin M Scott , Cristina Gutiérrez-Vázquez , Liliana M Sanmarco , Jessica A da Silva Pereira, Zhaorong Li , Agustín Plasencia , Patrick Hewson, Laura M Cox, Madelynn O’Brien, Steven K Chen, Pedro M Moraes-Vieira, Belinda S W Chang, Sergio G Peisajovich , Francisco J Quintana
PLoS Pathog 2021 May 6;17(5):e1009557.
Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection
Tiffany Lin, Daisy Quellier, Jeffrey Lamb, , Pankaj Baral, Felix Bock, , , Gerald Pier, Isaac Chiu, Mihaela Gadjeva
Proc Natl Acad Sci 2021 May 11;118(19):e2016146118
Reversed-engineered human alveolar lung-on-a-chip model
Di Huang, Tingting Liu, Junlong Liao, Sushila Maharjan, Xin Xie, Montserrat Pérez, Ingrid Anaya, Shiwei Wang, Alan Tirado Mayer, Zhixin Kang, Weijia Kong, Valerio Luca Mainardi, Carlos Ezio Garciamendez-Mijares, Germán García Martínez, Matteo Moretti, Weijia Zhang, Zhongze Gu, Amir M Ghaemmaghami, Yu Shrike Zhang
Science 2021 Apr 23;372(6540):eabf1230.
Barcoded viral tracing of single-cell interactions in central nervous system inflammation
Iain C Clark, Cristina Gutiérrez-Vázquez, Michael A Wheeler, Zhaorong Li, Veit Rothhammer, Mathias Linnerbauer, Liliana M Sanmarco, Lydia Guo, Manon Blain, Stephanie E J Zandee, Chun-Cheih Chao, Katelyn V Batterman, Marius Schwabenland, Peter Lotfy, Amalia Tejeda-Velarde, Patrick Hewson, Carolina Manganeli Polonio, Michael W Shultis, Yasmin Salem, Emily C Tjon, Pedro H Fonseca-Castro, Davis M Borucki, Kalil Alves de Lima, Agustin Plasencia, Adam R Abate, Douglas L Rosene, Kevin J Hodgetts Marco Prinz, Jack P Antel, Alexandre Prat, Francisco J Quintana
Nature 2021 Feb;590(7846):473-479. doi: 10.1038/s41586-020-03116-4. Epub 2021 Jan 6.
Gut-licensed IFNγ + NK cells drive LAMP1 + TRAIL + anti-inflammatory astrocytes
Liliana M Sanmarco, Michael A Wheeler, Cristina Gutiérrez-Vázquez, Carolina Manganeli Polonio, Mathias Linnerbauer, Felipe A Pinho-Ribeiro, Zhaorong Li, Federico Giovannoni, Katelyn V Batterman, Giulia Scalisi, Stephanie E J Zandee, Evelyn S Heck, Moneera Alsuwailm, Douglas L Rosene, Burkhard Becher, Isaac M Chiu, Alexandre Prat, Francisco J Quintana
Mov Disord 2021 Feb;36(2):348-359.doi: 10.1002/mds.28346. Epub 2020 Oct 26.
Upregulation of Cellular Palmitoylation Mitigates α-Synuclein Accumulation and Neurotoxicity
Ann Neurol 2021 Jan;89(1):74-90. doi: 10.1002/ana.25920. Epub 2020 Oct 23.
Silke Nuber, Alice Y Nam, Molly M Rajsombath , Haley Cirka , Xiaoping Hronowski , Junmin Wang , Kevin Hodgetts , Liubov S Kalinichenko , Christian P Müller , Vera Lambrecht , Jürgen Winkler , Andreas Weihofen , Thibaut Imberdis , Ulf Dettmer , Saranna Fanning , Dennis J Selkoe
2020:
Neuron 2020 Oct 14;108(1):128-144.e9.
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury
William Renthal, Ivan Tochitsky, Lite Yang, Yung-Chih Cheng, Emmy Li, Riki Kawaguchi, Daniel H Geschwind, Clifford J Woolf
Mov Disord 2020 May;35(5):760-773. doi: 10.1002/mds.27994. Epub 2020 Feb 8.
Lysosome and Inflammatory Defects in GBA1-Mutant Astrocytes Are Normalized by LRRK2 Inhibition
Anwesha Sanyal , Mark P DeAndrade , Hailey S Novis , Steven Lin , Jianjun Chang, Nathalie Lengacher , Julianna J Tomlinson , Malú G Tansey , Matthew J LaVoie
Nature 2020 Feb;578(7796):593-599. doi: 10.1038/s41586-020-1999-0. Epub 2020 Feb 12.
MAFG-driven astrocytes promote CNS inflammation
Michael A Wheeler, Iain C Clark, Emily C Tjon, Zhaorong Li, Stephanie E J Zandee, Charles P Couturier, Brianna R Watson, Giulia Scalisi, Sarah Alkwai, Veit Rothhammer, Assaf Rotem, John A Heyman, Shravan Thaploo, Liliana M Sanmarco, Jiannis Ragoussis, David A Weitz , Kevin Petrecca, Jeffrey R Moffitt, Burkhard Becher, Jack P Antel, Alexandre Prat, Francisco J Quintana
Nature Neuroscience volume 23, pages939–951(2020)
AHR is a Zika virus host factor and a candidate target for antiviral therapy
Federico Giovannoni, Irene Bosch, Carolina Manganeli Polonio, María F. Torti, Michael A. Wheeler, Zhaorong Li, Leonardo Romorini, María S. Rodriguez Varela, Veit Rothhammer, Andreia Barroso, Emily C. Tjon, Liliana M. Sanmarco, Maisa C. Takenaka, Seyed Mohamad Sadegh Modaresi, Cristina Gutiérrez-Vázquez, Nágela Ghabdan Zanluqui, Nilton Barreto dos Santos, Carolina Demarchi Munhoz, Zhongyan Wang, Elsa B. Damonte, David Sherr, Lee Gehrke, Jean Pierre Schatzmann Peron, Cybele C. Garcia & Francisco J. Quintana
Biofabrication 10 November 2020 https://doi.org/10.1088/1758-5090/abc1be
Yi-Chen Li, Yasamin Jodat, Roya Samanipour, Giulio Zorzi, Kai Zhu, Minoru Hirano, Karen Chang, Adnan Arnaout, Shabir Hassan, Navneet Matharu, Ali Khademhosseini, Mina Hoorfar, Su Ryon Shin.
Small. 23 October 2020 https://doi.org/10.1002/smll.202004258
Junmin Lee, Shreya Mehrotra, Elaheh Zare-Eelanjegh, Raquel Rodrigues, Alireza Akbarinejad, David Ge, Luca Amato, Kiavash Kiaee, YongCong Fang, Aliza Rosenkranz, Wendy Keung, Biman B. Mandal, Ronald A Li, Ting Zhang, HeaYeon Lee, Mehmet Remzi Dokmeci, Yu Shrike Zhang, Ali Khademhosseini, Su Ryon Shin.
Adv Sci (Weinh) 2020 Jan 10;7(5):1901878. doi: 10.1002/advs.201901878. eCollection 2020 Mar.
A 3D-Printed Hybrid Nasal Cartilage with Functional Electronic Olfaction
Yasamin A Jodat , Kiavash Kiaee , Daniel Vela Jarquin , Rosakaren Ludivina De la Garza Hernández 1, Ting Wang , Sudeep Joshi , Zahra Rezaei , Bruna Alice Gomes de Melo , David Ge , Manu S Mannoor , Su Ryon Shin
Dev Cell 2020 Feb 24;52(4):525-540.e5. doi: 10.1016/j.devcel.2020.01.026.
Gemma L Johnson, Erick J Masias, Jessica A Lehoczky
Nat Commun 2020 Mar 9;11(1):1267. doi: 10.1038/s41467-020-14997-4.
Complexation-inducedresolution enhancement of 3D-printed hydrogel constructs
Jiaxing Gong , Carl C L Schuurmans , Anne Metje van Genderen , Xia Cao , Wanlu Li , Feng Cheng , Jacqueline Jialu He , Arturo López , Valentin Huerta , Jennifer Manríquez , Ruiquan Li , Hongbin Li , Clément Delavaux , Shikha Sebastian , Pamela E Capendale , Huiming Wang , Jingwei Xie , Mengfei Yu , Rosalinde Masereeuw , Tina Vermonden , Yu Shrike Zhang
DEVELOPMENT 2020 Jun26; 14(12):dev18344. doi: 10.1242
Differentiation of the human PAX7-positive myogenic precursors/satellite cell lineage in vitro
Ziad Al Tanoury, Jyoti Rao, Olivier Tassy, Bénédicte Gobert, Svetlana Gapon, Jean-Marie Garnier, Erica Wagner, Aurore Hick, Arielle Hall, Emanuela Gussoni, Olivier Pourquié
Alzheimers Res Ther. 2020 Jan 13;12(1):12
Crehan H, Liu B, Kleinschmidt M, Rahfeld JU, Le KX, Caldarone BJ, Frost JL, Hettmann T, Hutter-Paier B, O’Nuallain B, Park MA, DiCarli MF, Lues I, Schilling S, Lemere CA
iScience 2020 Aug 21;23(8):101420. doi: 10.1016/j.isci.2020.101420. Epub 2020 Jul 29.
Ailiang Zeng , Zhiyun Wei , Rosalia Rabinovsky , Hyun Jung Jun , Rachid El Fatimy , Evgeny Deforzh , Ramil Arora , Yizheng Yao , Shun Yao , Wei Yan , Erik J Uhlmann , Alain Charest , Yongping You , Anna M Krichevsky
Cell Rep. 2020 Feb 18;30(7):2065-2074.e4. doi: 10.1016/j.celrep.2020.01.073. PMID: 32075753
Lucero R, Zappulli V, Sammarco A, Murillo OD, Cheah PS, Srinivasan S, Tai E, Ting DT, Wei Z, Roth ME, Laurent LC, Krichevsky AM, Breakefield XO, Milosavljevic A.
Methods 2020 Apr 8;S1046-2023(20)30047-5. doi: 10.1016/j.ymeth.2020.04.003.
Tingting Liu , Qiong Liu , Ingrid Anaya , Di Huang , Weijia Kong , Luis S Mille , Yu Shrike Zhang
Front Neurosci 2020 May 15;14:442. doi: 10.3389/fnins.2020.00442. eCollection 2020.
Anwesha Sanyal , Hailey S Novis , Emile Gasser , Steven Lin , Matthew J LaVoie
Adv Funct Mater 2020 Mar 17;30(12):1907436. doi: 10.1002/adfm.201907436. Epub 2020 Jan 20.
Shreya Mehrotra , Bruna A G de Melo , Minoru Hirano , Wendy Keung , Ronald A Li , Biman B Mandal , Su Ryon Shin
J Am Soc Nephrol 2020 Jul;31(7):1479-1495. doi: 10.1681/ASN.2019101032. Epub 2020 Jun 15.
Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis
Di Feng, Mukesh Kumar, Jan Muntel , Susan B Gurley , Gabriel Birrane , Isaac E Stillman , Lai Ding, Minxian Wang , Saima Ahmed , Johannes Schlondorff , Seth L Alper , Tom Ferrante , Susan L Marquez , Carlos F Ng, Richard Novak , Donald E Ingber , Hanno Steen , Martin R Pollak
Acta Neuropathol 2020 Mar;139(3):503-526. doi: 10.1007/s00401-019-02114-9. Epub 2019 Dec 18.
Grant T Corbett, Zemin Wang, Wei Hong, Marti Colom-Cadena, Jamie Rose, Meichen Liao, Adhana Asfaw, Tia C Hall , Lai Ding , Alexandra DeSousa , Matthew P Frosch , John Collinge , David A Harris, Michael S Perkinton, Tara L Spires-Jones, Tracy L Young-Pearse, Andrew Billinton, Dominic M Walsh
Int J Mol Sci 2020 Jul 22;21(15):5193. doi: 10.3390/ijms21155193.
Elizabeth Terry-Kantor , Arati Tripathi , Thibaut Imberdis , Zachary M LaVoie , Gary P H Ho , Dennis Selkoe , Saranna Fanning , Nagendran Ramalingam , Ulf Dettmer
Mov Disord 2020 Oct 26. doi: 10.1002/mds.28346. Online ahead of print.
Upregulation of Cellular Palmitoylation Mitigates α-Synuclein Accumulation and Neurotoxicity
Gary P H Ho , Nagendran Ramalingam , Thibaut Imberdis , Erin C Wilkie , Ulf Dettmer , Dennis J Selkoe
2019:
Cell 2019 Dec 12;179(7):1483-1498.e22. doi: 10.1016/j.cell.2019.11.016. Epub 2019 Dec 5.
Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS
Chun-Cheih Chao, Cristina Gutiérrez-Vázquez, Veit Rothhammer, Lior Mayo, Michael A Wheeler, Emily C Tjon, Stephanie E J Zandee, Manon Blain, Kalil Alves de Lima, Maisa C Takenaka, Julian Avila-Pacheco, Patrick Hewson, Lei Liu, Liliana M Sanmarco, Davis M Borucki, Gabriel Z Lipof, Sunia A Trauger, Clary B Clish, Jack P Antel, Alexandre Prat, Francisco J Quintana
Nat Neurosci 2019 May;22(5):729-740. doi: 10.1038/s41593-019-0370-y. Epub 2019 Apr 8.
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39
Maisa C Takenaka, Galina Gabriely, Veit Rothhammer, Ivan D Mascanfroni, Michael A Wheeler, Chun-Cheih Chao, Cristina Gutiérrez-Vázquez, Jessica Kenison, Emily C Tjon, Andreia Barroso, Tyler Vandeventer, Kalil Alves de Lima, Sonja Rothweiler, Lior Mayo, Soufiene Ghannam, Stephanie Zandee, Luke Healy, David Sherr, Mauricio F Farez , Alexandre Prat , Jack Antel, David A Reardon, Hailei Zhang, Simon C Robson, Gad Getz, Howard L Weiner, Francisco J Quintana
Cell 2019 Jan 24;176(3):581-596.e18. doi: 10.1016/j.cell.2018.12.012. Epub 2019 Jan 17.
Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation
Michael A Wheeler, Merja Jaronen, Ruxandra Covacu, Stephanie E J Zandee, Giulia Scalisi, Veit Rothhammer, Emily C Tjon, Chun-Cheih Chao, Jessica E Kenison, Manon Blain, Vijayaraghava T S Rao, Patrick Hewson, Andreia Barroso, Cristina Gutiérrez-Vázquez, Alexandre Prat, Jack P Antel, Russ Hauser, Francisco J Quintana
2018:
Transl Psychiatry 2018 Nov 8;8(1):245.
Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression
Priya Srikanth , Valentina N Lagomarsino, Richard V Pearse , Meichen Liao, Sulagna Ghosh, Ralda Nehme, Nicholas Seyfried, Kevin Eggan, Tracy L Young-Pearse
Nat Commun 2018 Nov 1;9(1):4578.
Acute microglia ablation induces neurodegeneration in the somatosensory system
Stephen J Rubino, Lior Mayo, Isabella Wimmer, Victoria Siedler, Florian Brunner, Simon Hametner, Asaf Madi, Amanda Lanser, Thais Moreira, Dustin Donnelly, Laura Cox, Rafael Machado Rezende, Oleg Butovsky, Hans Lassmann, Howard L Weiner
Acta Neuropathol 2018 Oct;136(4):537-555.
MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways
Rachid El Fatimy, Shaomin Li, Zhicheng Chen, Tasnim Mushannen, Sree Gongala, Zhiyun Wei, Darrick T Balu, Rosalia Rabinovsky, Adam Cantlon, Abdallah Elkhal, Dennis J Selkoe, Kai C Sonntag, Dominic M Walsh, Anna M Krichevsky
EMBO Mol Med 2018 Sep;10(9):e8931.
Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β
Huixin Xu , Molly M Rajsombath , Pia Weikop , Dennis J Selkoe
Nat Commun 2018 Jul 11;9(1):2676.
An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease
Ming Jin, Brian O’Nuallain, Wei Hong, Justin Boyd, Valentina N Lagomarsino, Tiernan T O’Malley, Wen Liu, Charles R Vanderburg, Matthew P Frosch, Tracy Young-Pearse, Dennis J Selkoe, Dominic M Walsh
Nat Commun 2018 Aug 8;9(1):3151
γδ T cells control humoral immune response by inducing T follicular helper cell differentiation
Rafael M Rezende, Amanda J Lanser, Stephen Rubino, Chantal Kuhn, Nathaniel Skillin, Thais G Moreira, Shirong Liu, Galina Gabriely, Bruna A David, Gustavo B Menezes, Howard L Weiner